Proline-rich polypeptides bound to rat prostatic binding protein. The primary structure of the two main components, proline-rich polypeptides IV and V.
نویسندگان
چکیده
منابع مشابه
Study of a proline-rich polypeptide bound to the prostatic binding protein of rat ventral prostate.
A proline-rich polypeptide is associated with prostatic binding protein, a major androgen-dependent protein described previously in the rat ventral prostate. This polypeptide has been purified. Its molecular weight estimated by gel filtration is about 8500, but a markedly lower value (3300) is obtained by sodium dodecyl sulfate-urea polyacrylamide gel electrophoresis. Isoelectric focusing on th...
متن کاملPrimary structure of a proline-rich zein and its cDNA.
Eighty-five cDNA clones for gamma-zein (proline-rich zein) from a cDNA expression library were isolated using specific antibody and cDNA probes. Nucleotide sequences of seven independent clones were determined and found to be identical in regions where they overlapped. The primary structure of the mature protein, determined from the sequence of one near full-length clone, consists of 204 amino ...
متن کاملThe structure and function of proline-rich regions in proteins.
Proline is a very unusual amino acid, in that the side-chain is cyclized back on to the backbone amide position. This has three important consequences. First, the backbone conformation of proline itself is very restricted. The available backbone sb dihedral angles are limited to a small range around = -65 [1,2] (Figure 1). Similar restrictions do not apply to i/, which is able to populate eithe...
متن کاملThe unique proline-rich domain of parotid proline-rich proteins functions in secretory sorting.
When expressed in pituitary AtT-20 cells, parotid proline-rich proteins enter the regulated pathway. Because the short N-terminal domain of a basic proline-rich protein is necessary for efficient export from the ER, it has not been possible to evaluate the role of this polypeptide segment as a sorting signal for regulated secretion. We now show that addition of the six-amino acid propeptide of ...
متن کاملProtective Effects of Proline–Rich Peptide in a Rat Model of Alzheimer Disease: An Electrophysiological Study
Introduction: Alzheimer disease (AD) is the most common form of dementia in the elderly that slowly destroys memory and cognitive functions. The disease has no cure and leads to significant structural and functional brain abnormalities. To facilitate the treatment of this disease, we aimed to investigate proline-rich peptide (PRP-1) action of hypothalamus on hippocampal (HP) neurons and dynamic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1983
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(17)43846-4